A village was foremost mentioned in the Domesday Book, in which it was known as Geneshalle.

A Wellington to Stafford Railway line another time ran through the village, however these are currently closed & dismantled & its route occurs as pathway.

Notes of interest include: St. Lawrence Church, which dates from either Norman times and stands above a places of an sooner Saxon church. Coton Mill, in which these are claimed self-raising flour was invented The Shropshire Union Canal Rock star Ozzy Osbourne lived briefly in the village The Revolutions per minute. Adam Blakeman, the Puritan minister who founded a early U.s. town of Stratford, Connecticut, was born inside Gnosall inside 1596.

Nearby is Gnosall Heath.